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Search Results for " nogo receptor "

3

抑制剂 & 化合物

10

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
TP1989L	Nogo-66 (1-40) aceate ( 475221-20-6 Free base)
	Nogo-66 (1-40) aceate (475221-20-6 Free base) 是对应于 Nogo-66 残基 1 - 40 的肽片段，Nogo-66 是抑制轴突生长的髓磷脂蛋白 Nogo 的结构域。Nogo-66 (1-40) aceate 作为 Nogo-66 受体 (NgR) 的竞争性拮抗剂，阻断 Nogo-66 和 CNS 髓磷脂诱导的轴突生长抑制，但不会减少髓磷脂相关糖蛋白 (MAG) 体外抑制神经突生长。Nogo-66 (1-40) aceate 促进体内脊髓损伤后半切脊髓轴突的再生和运动恢复。
TP1989	NEP(1-40) Nogo-66 (1-40)
	Peptide fragment corresponding to residues 1 - 40 of Nogo-66, the domain of the myelin protein Nogo that inhibits axonal outgrowth. Acts as a competitive antagonist at the Nogo-66 receptor (NgR); blocks Nogo-66- and CNS myelin-induced inhibition of axonal
T81685	NEP(1-40) TFA
	NEP(1-40) TFA 是一种Nogo-66 受体 (NgR) 的肽类拮抗剂，其作用机制为通过抑制髓蛋白所引发的损伤逆转，限制小胶质细胞形态分布的变化。

化合物

Nogo-66 (1-40) aceate ( 475221-20-6 Free base)

Cat.No: TP1989L

Cat.No: TP1989

Synonym: Nogo-66 (1-40)

Cat.No: T81685

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-01200	Nogo Receptor/RTN4R Protein, Cynomolgus, Recombinant (His) NGR,NOGOR,RTN4R,NgR1,Nogo receptor	Cynomolgus	HEK293 Cells
	NOGO Receptor 1 (RTN4R) regulates axonal growth, as well as axon regeneration after injury. The gene maps to the 22q11.2 schizophrenia susceptibility locus and is thus a strong functional and positional candidate gene.RTN4R may modulate the genetic risk or clinical expression of schizophrenia in a subset of patients and identify additional studies that will be necessary to clarify the role of RTN4R in psychiatric phenotypes.
TMPJ-00295	NgR Protein, Mouse, Recombinant (hFc) Nogo-66 Receptor,Nogo Recepto...	Mouse	HEK293 Cells
	Nogo Receptor (NgR) is a glycosylphosphoinositol (GPI)-anchored protein that belongs to the Nogo recptor family. Human NgR is predominantly expressed in neurons and their axons in the central nervous systems. As a receptor for myelin-derived proteins Nogo, myelin-associated glycoprotein (MAG) and myelin oligodendrocyte glycoprotein (OMG), NgR mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. NgR may be prop...
TMPJ-00277	NgR3 Protein, Human, Recombinant (His) NGRL2,Nogo Receptor-Like 2,Reticulon-4	Human	HEK293 Cells
	Nogo-66 Receptor-Related Protein 3 (NgR3) has primary structures with NgR2 (NgRH1, NgRL3) and biochemical properties that are homologous to Nogo-66 receptor (NgR), and constitute a novel neuronal receptor protein family. NgR is GPI-anchored and contains eight leucine-rich repeats (LRR), it is the neuronal receptor for the myelin- associated proteins Nogo-A, OMgp (oligodendrocyte myelin glycoprotein), and MAG (myelin-associated glycoprotein) and mediates the inhibition of CNS axonal regeneration ...
TMPY-01163	Nogo Receptor/RTN4R Protein, Mouse, Recombinant (His) Rtn4r,NgR,NgR1,reticulon 4 receptor,NOGOR	Mouse	HEK293 Cells
	Nogo Receptor/RTN4R Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47 kDa and the accession number is Q99PI8.
TMPY-03144	Nogo Receptor/RTN4R Protein, Human, Recombinant (His) NGR,reticulon 4 receptor,NOGOR	Human	HEK293 Cells
	Nogo Receptor/RTN4R Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.8 kDa and the accession number is Q9BZR6.
TMPY-01056	Nogo Receptor/RTN4R Protein, Human, Recombinant (His & hFc) NOGOR,reticulon 4 receptor,NGR	Human	HEK293 Cells
	Nogo Receptor/RTN4R Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 73 kDa and the accession number is Q9BZR6.
TMPY-01221	Nogo Receptor/RTN4R Protein, Mouse, Recombinant (His & hFc) NgR1,reticulon 4 receptor,NgR,Rtn4r,NOGOR	Mouse	HEK293 Cells
	Nogo Receptor/RTN4R Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 73.8 kDa and the accession number is Q99PI8.
TMPH-01610	LINGO1 Protein, Human, Recombinant (His)	Human	E. coli
	Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination. Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development.
TMPH-02753	LINGO1 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination. Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development. LINGO1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The pre...
TMPY-02001	RTN4 Protein, Human, Recombinant (GST) UNG1,NOGO,reticulon 4,RTN4-A,Nbla00271,NOGO	Human	E. coli
	Reticulon-4, also known as Foocen, Neurite outgrowth inhibitor, Nogo protein, Neuroendocrine-specific protein, Neuroendocrine-specific protein C homolog, RTN-x, Reticulon-5 and RTN4, is a multi-pass membrane protein that contains one reticulon domain. Isoform 1 of RTN4 is specifically expressed in brain and testis and weakly in heart and skeletal muscle. Isoform 2 of RTN4 is widely expressed except for the liver. Isoform 3 of RTN4 is expressed in brain, skeletal muscle and adipocytes. Isoform 4 ...

重组蛋白

Nogo Receptor/RTN4R Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-01200

Species: Cynomolgus

Expression System: HEK293 Cells

NgR Protein, Mouse, Recombinant (hFc)

Cat.No: TMPJ-00295

Species: Mouse

Expression System: HEK293 Cells

NgR3 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00277

Species: Human

Expression System: HEK293 Cells

Nogo Receptor/RTN4R Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01163

Species: Mouse

Expression System: HEK293 Cells

Nogo Receptor/RTN4R Protein, Human, Recombinant (His)

Cat.No: TMPY-03144

Species: Human

Expression System: HEK293 Cells

Nogo Receptor/RTN4R Protein, Human, Recombinant (His & hFc)

Cat.No: TMPY-01056

Species: Human

Expression System: HEK293 Cells

Nogo Receptor/RTN4R Protein, Mouse, Recombinant (His & hFc)

Cat.No: TMPY-01221

Species: Mouse

Expression System: HEK293 Cells

LINGO1 Protein, Human, Recombinant (His)

Cat.No: TMPH-01610

Species: Human

Expression System: E. coli

LINGO1 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02753

Species: Mouse

Expression System: E. coli

RTN4 Protein, Human, Recombinant (GST)

Cat.No: TMPY-02001

Species: Human

Expression System: E. coli

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